EVALUATION OF RAPID EXTRACTION AND ISOTHERMAL AMPLIFICATION TECHNIQUES FOR THE DETECTION OF LEISHMANIA DONOVANI DNA FROM SKIN LESIONS OF SUSPECTED CASES AT THE POINT OF NEED IN SRI LANKA

Abstract Background Leishmaniasis is a disease caused by vector-borne protozoans.In Sri Lanka, the cutaneous form of the disease is predominant, which is usually diagnosed using Giemsa-stained slit skin smear examination and by histology.However, the sensitivity of slit skin smears and histology are reportedly low.Moreover, facilities for the highl

IntroductionClonal hematopoiesis (CH) is characterized by the presence of hematopoietic stem cells (HSCs) with the potential of clonally expanding and giving rise to hematological malignancies.Clonal hematopoiesis of indeterminate potential (CHIP) is the outgrowth of a single HSC clone with an acquired somatic mutation in the absence of hematologic

We aimed to determine whether tocomin, an extract from palm oil that has a high tocotrienol content, was able to prevent diabetes-induced endothelial dysfunction.To induce type 1 diabetes streptozotocin (50 mg/kg) was injected into the tail vein of Wistar rats.Six weeks later the diabetic rats, and normal rats injected with citrate buffer, commence

BackgroundDisconnected consciousness describes a state in which subjective experience (i.e., consciousness) becomes isolated from the external world.It appears frequently during sleep or sedation, when subjective experiences remain vivid but are unaffected by external stimuli.Traditional methods of differentiating connected and disconnected conscio

Without certain adjustments to specifics of computer crime, as to a phenomenon of global proportions, detection, investigation and prosecution of this type of crime is almost impossible.Therefore, the need for setting up a legal framework Rolling for combating cyber crime has been identified, in order to define which activities related to informati